Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 130
  • Home
  • Print this page
  • Email this page
REVIEW ARTICLE
Year : 2015  |  Volume : 1  |  Issue : 2  |  Page : 65-72

Molecular oncology update: Breast cancer gene expression profiling


1 Max Cancer Center, Max Hospital, New Delhi, India
2 MolQ Laboratory, Molecular Quest Healthcare Pvt. Ltd., Gurgaon, Haryana, India
3 MolQ Laboratory, Molecular Quest Healthcare Pvt. Ltd., Gurgaon, Haryana, India; Department of Biochemistry and Molecular Biology, University of Maryland, Baltimore, MD; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Correspondence Address:
Amit Verma
Max Cancer Center, Max Hospital, New Delhi
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2454-6798.173282

Rights and Permissions

Molecular Oncology has paved its way in the comprehensive cancer care, and its burgeoning role especially in the discovery of novel cellular targets is responsible for emergence of the new Paradigm called "Genomic Paradigm", a shift from the old age "Clinico-Pathological Paradigm". In breast cancer, till recently clinical decisions, prognostications, and predictions were based solely upon histopathologic analysis, or one or a small numbers of genes or their expressions (proteins) in the tumor tissue. With the advent of newer technologies like microarray, which allows us to read the "Molecular Signature" of an individual patient's tumor, the molecular information is exploited for novel targeted treatments and new biomarkers identification. This has led to better classification of cancers for prognostication and treatment selection. In this review we have summarized various Genomic Expression Profiling (GEP) which are available commercially or in different developmental phases.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1883    
    Printed59    
    Emailed1    
    PDF Downloaded899    
    Comments [Add]    
    Cited by others 1    

Recommend this journal